The nucleotide-binding domain of the Zn2+-transporting P-type ATPase from Escherichia coli carries a glycine motif that may be involved in binding of ATP.

Academic Dissertation Helsinki 2004 INTRODUCING WILSON DISEASE MUTATIONS INTO ZNTA Studies on the nucleotide and metal-binding sites of a bacterial zinc-translocating P-type ATPase

(2002) Introducing Wilson disease mutations into the zinc-transporting P-type ATPase of Escherichia coli. The mutation P634L in the " hinge " motif (GDGXNDXP) perturbs the formation of the E 2-P state. Eur. The nucleotide-binding domain of the Zn 2+-transporting P-type ATPase from Escherichia coli carries a glycine motif that may be involved in binding of ATP. Biochem. J. 377: 95-105 In additio...

Nucleotide recognition by CopA, a Cu+-transporting P-type ATPase.

Heavy metal pumps constitute a large subgroup in P-type ion-transporting ATPases. One of the outstanding features is that the nucleotide binding N-domain lacks residues critical for ATP binding in other well-studied P-type ATPases. Instead, they possess an HP-motif and a Gly-rich sequence in the N-domain, and their mutations impair ATP binding. Here, we describe 1.85 A resolution crystal struct...

Cloning of Binding Domain of Clostridium botlllinum Toxin Type A in Escherichia coli

Structure of rho factor: an RNA-binding domain and a separate region with strong similarity to proven ATP-binding domains.

The domain structure of rho protein, a transcription termination factor of Escherichia coli, was analyzed by oligonucleotide site-directed mutagenesis and chemical modification methods. The single cysteine at position 202, previously thought to be essential for rho function, was changed to serine or to glycine with no detectable effects on the protein's hexameric structure, RNA-binding ability,...

Analysis of Sars-CoV-2 RBD Mutations in Khuzestan Province, Iran—A Retrospective Study, 2021

Background and Objective: One of the main reasons for the ongoing pandemic is the substitutions in the Receptor binding domain(RBD), which is involved in binding to the ACE2 receptor. Methods: Oro-nasopharyngeal swabs were collected from 41 confirmed patients between September 2020 and May 2021 to analyze the mutations of SARS-CoV-2 RBD in Khuzestan Province. Bi-Directional sequencing was use...